Hypotensive Activity and Toxicology of Constituents from Bombax ceiba Stem Bark.

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Hypotensive activity and toxicology of constituents from Bombax ceiba stem bark.

A novel constituent, shamimicin, 1"', 1"""'-bis-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,7-dihydroxy-5-O-xylopyranosyloxy-2H-1-benzopyran along with lupeol, which possesses potent hypotensive activity, has been isolated from Bombax ceiba stem bark. BCBMM--one of the most active hypotensive fractions has revealed its adverse effects on heart, liver and kidneys of mice at the dose of 1000 mg/kg/d.

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Chemical constituents from stem bark and roots of Clausena anisata.

Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of ...

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Evaluation of Rbc Membrane Stabilization and Antioxidant Activity of Bombax Ceiba in an in Vitro Method

This study reports the human red blood cells (HRBC) and sheep red blood cells (SRBC) membrane stabilizing property and the antioxidizing property of ethyl acetate soluble fraction of the gynaceum part of Bombax ceiba. The probable mode by which Bombax ceiba mediates its effects on inflammatory conditions was studied on HRBC & SRBC exposed to hypotonic solution. The results of the study revealed...

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ژورنال

عنوان ژورنال: Biological and Pharmaceutical Bulletin

سال: 2003

ISSN: 0918-6158,1347-5215

DOI: 10.1248/bpb.26.41